Search on: NAD-DEPENDENT 3-HYDROXY-3-METHYLGLUTARYL COA-REDUCTASE 
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Descriptor English:   Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent 
Descriptor Spanish:   Hidroximetilglutaril-CoA Reductasas NAD-Dependientes 
Descriptor Portuguese:   Hidroximetilglutaril-CoA Redutases NAD-Dependentes 
Synonyms English:   3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent
HMG CoA Reductase, NAD-Dependent
Hydroxymethylglutaryl CoA Reductase, NAD-Dependent
CoA-Reductase, NAD-Dependent 3-Hydroxy-3-methylglutaryl
HMG CoA Reductase, NAD Dependent
HMG CoA Reductases, NAD Dependent
Hydroxymethylglutaryl CoA Reductase, NAD Dependent
NAD-Dependent 3-Hydroxy-3-methylglutaryl CoA-Reductase
NAD-Dependent Hydroxymethylglutaryl-CoA Reductases
HMG CoA Reductases, NAD-Dependent  
Tree Number:   D08.811.682.047.820.150.415.250
Definition English:   Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH. 
Indexing Annotation English:   do not confuse with HYDROXYMETHYLGLUTARYL-COA-REDUCTASES, NADP-DEPENDENT
History Note English:   2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   36098 
Unique Identifier:   D025781 

Occurrence in VHL:
 

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